Product

Product

EGFR Exon 20 T790 Primer Set

Epidermal growth factor receptor (EGFR) is one of the most frequently amplified, mutated and/or overexpressed genes in human malignancies. Inactivation of EGFR kinase with tyrosine kinase inhibitors (TKIs), such as gefitinib (Iressa) and erlotinib (Tarceva), suppresses signal transduction pathways which control tumor cell growth, proliferation, and resistance to apoptosis. TKIs therapy have shown a significant symptom benefit and prolong survival on the treatment of Non-Small Cell Lung Cancer (NSCLC) patients with somatics mutations in the EGFR gene. Therefore, detection of the somatic mutations in the EGFR gene may provide a more accurate response to the cancer patients receiving TKIs therapy. EGFR exon 20 T790 primer set have the function to enrich mutation type of EGFR gene and allows to detect target codon T790 on DNA samples.

01

Product Specification

  • Gene Name

    EGFR epidermal growth factor receptor

  • Catalog

    20 tests: EGFR-025-0020
    50 tests: EGFR-025-0050

  • Official Symbol

    EGFR

  • Alternative Name

    EGFR; Epidermal growth factor receptor; erbb 1; Erbb; Erbb1; ERBB1; HER1; mENA; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; Receptor tyrosine protein kinase ErbB 1; Receptor tyrosine protein kinase ErbB1; Receptor tyrosineprotein kinase ErbB-1; Urogastrone; wa2; Wa5; proto-oncogene c-ErbB -1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; ERBB; HER1; PIG61

  • GeneID

    1956

  • Uniprot ID

    P00533

  • Target Codon

    T790

  • Gene Range

    782~823 aa

  • Purity Detail

    Purified by High-performance liquid chromatography

  • Recommend PCR Condition

    95°C, 10mins;
    94°C, 1mins–>65°C, 3mins–>57°C, 1mins–>72°C, 1mins (x45 cycles);
    72°C, 10mins;
    10°C, ∞

  • Shipping Condition

    4°C

  • Long Term Storage

    Stable for up to one year when store at -20°C. Avoid freeze/thaw cycles.

  • Data

    EGFR-EXON-20-T790EGFR T790

  • Datasheet

    EGFR Exon 20 T790 Primer Set datasheet

  • Order Now

02

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